Table 4.
Prediction of Lymphoedema (defined by RAVI ≥ 10) by 36 months.
| Univariate | Multivariable | ||||
|---|---|---|---|---|---|
| Variable | OR (95% CI) | p-value | OR (95% CI) | p-value | Score |
| RAVI at 1 month | <0.001 | <0.001 | |||
| <3% | 1 (–) | 1 (–) | 0 | ||
| ≥3–<5% | 1.37 (0.82–2.30) | 1.48 (0.86–2.56) | 0.5 | ||
| ≥5–<10% | 4.08 (2.66–6.25) | 5.27 (3.30–8.41) | 1.5 | ||
| >10% | 5.54 (2.33–13.16) | 6.60 (2.52–17.31) | 2 | ||
| LBCQ checklist swelling at pre-surgery (yes) | 2.06 (1.22–3.49) | 0.007 | – | – | |
| Age (per year increase) | 1.01 (1.00–1.03) | 0.021 | – | – | |
| BMI at pre-surgery | 0.017 | 0.10 | |||
| ≤25 | 1 (–) | 1 (–) | 0 | ||
| >25–≤30 | 1.22 (0.83–1.79) | 1.18 (0.75–1.86) | 0 | ||
| >30 | 1.72 (1.17–2.51) | 1.63 (1.03 to +2.57) | 0.5 | ||
| ER status (negative) | 1.32 (0.91–1.91) | 0.14 | 1.35 (0.86–2.13) | 0.19 | 0.5 |
| Pos nodes(n) (per node inc) | <0.001 | <0.001 | |||
| ≤3 | 1 (–) | 1 (– | 0 | ||
| 4–9 | 1.28 (0.87–1.89) | 1.41 (0.87–2.27) | 0.5 | ||
| ≥10 | 2.77 (1.87–4.11) | 3.05 (1.89–4.93) | 1 | ||
| Chemotherapy (CT) | 0.015 | 0.008 | |||
| No CT | 1 (–) | 1 (–) | 0.5 | ||
| CT with no taxane | 0.61 (0.30–1.25) | 0.54 (0.23–1.24) | 0 | ||
| CT with taxane | 1.41 (1.01–1.98) | 1.57 (1.04–2.38) | 1 | ||
| Radiotherapy (RT) | 0.015 | ||||
| No RT | 1 (–) | – | – | – | |
| Local RT only | 1.51 (0.94–2.43) | ||||
| Regional LN RT | 1.99 (1.23–3.20) | ||||
| Stage | <0.001 | ||||
| ≤2 | 1 (–) | – | – | – | |
| 3 | 1.79 (1.32–2.42) | ||||
| B3 at pre-surgery | 0.39 | ||||
| 0–1 (little to no swelling) | 1 (–) | – | – | – | |
| 2–4 (some to considerable swelling) | 1.28 (0.73–2.24) | ||||