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. 2020 May 4;123(1):17–25. doi: 10.1038/s41416-020-0844-4

Table 4.

Prediction of Lymphoedema (defined by RAVI ≥ 10) by 36 months.

Univariate Multivariable
Variable OR (95% CI) p-value OR (95% CI) p-value Score
RAVI at 1 month <0.001 <0.001
 <3% 1 (–) 1 (–) 0
 ≥3–<5% 1.37 (0.82–2.30) 1.48 (0.86–2.56) 0.5
 ≥5–<10% 4.08 (2.66–6.25) 5.27 (3.30–8.41) 1.5
 >10% 5.54 (2.33–13.16) 6.60 (2.52–17.31) 2
LBCQ checklist swelling at pre-surgery (yes) 2.06 (1.22–3.49) 0.007
Age (per year increase) 1.01 (1.00–1.03) 0.021
BMI at pre-surgery 0.017 0.10
 ≤25 1 (–) 1 (–) 0
 >25–≤30 1.22 (0.83–1.79) 1.18 (0.75–1.86) 0
 >30 1.72 (1.17–2.51) 1.63 (1.03 to +2.57) 0.5
ER status (negative) 1.32 (0.91–1.91) 0.14 1.35 (0.86–2.13) 0.19 0.5
Pos nodes(n) (per node inc) <0.001 <0.001
 ≤3 1 (–) 1 (– 0
 4–9 1.28 (0.87–1.89) 1.41 (0.87–2.27) 0.5
 ≥10 2.77 (1.87–4.11) 3.05 (1.89–4.93) 1
Chemotherapy (CT) 0.015 0.008
 No CT 1 (–) 1 (–) 0.5
 CT with no taxane 0.61 (0.30–1.25) 0.54 (0.23–1.24) 0
 CT with taxane 1.41 (1.01–1.98) 1.57 (1.04–2.38) 1
Radiotherapy (RT) 0.015
 No RT 1 (–)
 Local RT only 1.51 (0.94–2.43)
 Regional LN RT 1.99 (1.23–3.20)
Stage <0.001
 ≤2 1 (–)
 3 1.79 (1.32–2.42)
B3 at pre-surgery 0.39
 0–1 (little to no swelling) 1 (–)
 2–4 (some to considerable swelling) 1.28 (0.73–2.24)