Table 3.
Kidney biopsy findings
| Characteristics | Number |
|---|---|
| No. of glomeruli, n=23 | 16 (range, 6–30) |
| Obsolescent glomeruli, %, n=23 | 11 (range, 0–50) |
| FSGS lesions, %, n=21/23 | 64 (range, 12.5–100) |
| Collapsing lesions, %, n=18/21 | 50 (range, 4–100) |
| Interstitial fibrosis, %, n=23 | 18 (range, 0–50) |
| Interstitial infiltrate, n=23 | 18 (78%) |
| Interstitial edema, n=23 | 7 (30%) |
| Tubular microcyst dilation, n=23 | 15 (65%) |
| Acute tubular necrosis, n=23 | 15 (65%) |
| Arteriolar hyalinosis, n=23a | 15 (65%) |
| Definitive pathologic diagnosis | |
| FSGSb | 21 (91%) |
| Collapsing glomerulopathy | 18 |
| Including HIV-associated nephropathy | 9 |
| Not otherwise specified variant | 3 |
| Minimal change disease | 2 (9%) |
a
Arteriolar hyalinosis was scored as follows: +, mild; ++, moderate; +++, severe.
b
In one patient with HIV infection, kidney biopsy findings were consistent with not otherwise specified variant. In one patient, HIV-associated nephropathy lesions were associated with additional membranoproliferative GN lesions. In one patient, HIV-associated nephropathy lesions were associated with thrombotic microangiopathy lesions.