Table 2.
Effect of gestational age in the correlation between bilirubin values obtained from AJO-Neo and TSB and the predictive indices of AJO-Neo.
| Gestational age | Statistical Test | Parameters | Right thumb nail plate | Left thumb nail plate | |
|---|---|---|---|---|---|
| < 35 weeks | Linear regression analysis | Regression Coefficient (r) | 0.84 | 0.80 | |
| P value | < 0.0001 | < 0.0001 | |||
| Slope | 0.83 | 0.77 | |||
| Intercept | 1.52 | 1.14 | |||
| Bland altman analysis | Bias (95% CI) | 0.55(− 0.09 to 0.21) | 0.002(− 0.17 to 0.17) | ||
| Standard deviation | 1.62 | 1.83 | |||
| Limits of agreement | − 3.12 to 3.23 | − 3.58 to 3.59 | |||
| Accuracy | Above 95th percentile | Sensitivity | 0.84 | 0.69 | |
| Specificity | 0.99 | 0.99 | |||
| PPV | 0.93 | 0.89 | |||
| NPV | 0.98 | 0.98 | |||
| Above 75th percentile | Sensitivity | 0.71 | 0.57 | ||
| Specificity | 0.97 | 0.95 | |||
| PPV | 0.83 | 0.70 | |||
| NPV | 0.94 | 0.91 | |||
| Above 40th percentile | Sensitivity | 0.88 | 0.85 | ||
| Specificity | 0.90 | 0.88 | |||
| PPV | 0.80 | 0.76 | |||
| NPV | 0.94 | 0.93 | |||
| 35–38 weeks | Linear regression analysis | Regression Coefficient (r) | 0.77 | 0.74 | |
| P value | < 0.0001 | < 0.0001 | |||
| Slope | 0.64 | 0.60 | |||
| Intercept | 3.20 | 3.69 | |||
| Bland altman analysis | Bias (95% CI) | 0.67 (0.56 to 0.79) | 0.63 (0.51 to 0.75) | ||
| Standard deviation | 1.88 | 1.97 | |||
| Limits of agreement | − 3.01 to 4.36 | − 3.23 to 4.49 | |||
| Accuracy | Above 95th percentile | Sensitivity | 0.52 | 0.58 | |
| Specificity | 0.98 | 0.98 | |||
| PPV | 0.83 | 0.80 | |||
| NPV | 0.94 | 0.94 | |||
| Above 75th percentile | Sensitivity | 0.58 | 0.59 | ||
| Specificity | 0.94 | 0.94 | |||
| PPV | 0.75 | 0.75 | |||
| NPV | 0.88 | 0.88 | |||
| Above 40th percentile | Sensitivity | 0.72 | 0.71 | ||
| Specificity | 0.90 | 0.90 | |||
| PPV | 0.86 | 0.86 | |||
| NPV | 0.79 | 0.78 | |||
| > 38 weeks | Linear Regression Analysis | Regression Coefficient (r) | 0.81 | 0.82 | |
| P value | < 0.0001 | < 0.0001 | |||
| Slope | 0.54 | 0.52 | |||
| Intercept | 4.24 | 4.43 | |||
| Bland altman analysis | Bias (95% CI) | 0.50 (− 0.11 to 1.12) | 0.50 (− 0.11 to 1.11) | ||
| Standard deviation | 1.99 | 1.93 | |||
| Limits of agreement | − 3.28 to 4.29 | − 3.59 to 4.30 | |||
| Accuracy | Above 95th percentile | Sensitivity | 0.83 | 0.73 | |
| Specificity | 0.98 | 0.97 | |||
| PPV | 0.88 | 0.90 | |||
| NPV | 0.90 | 0.93 | |||
| Above 75th percentile | Sensitivity | 0.72 | 0.81 | ||
| Specificity | 0.96 | 0.96 | |||
| PPV | 0.88 | 0.90 | |||
| NPV | 0.90 | 0.83 | |||
| Above 40th percentile | Sensitivity | 0.79 | 0.79 | ||
| Specificity | 0.98 | 0.98 | |||
| PPV | 0.98 | 0.98 | |||
| NPV | 0.72 | 0.78 | |||