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. 2020 Jul 7;10:11149. doi: 10.1038/s41598-020-67981-9

Table 3.

The correlation between bilirubin values obtained from AJO-Neo and TSB along with predictive indices of AJO-Neo in neonates with AAP designated risk factors of hyperbilirubinemia.

Risk factors Statistical test Parameters Right thumb nail plate Left thumb nail plate
ABO incompatibility Linear regression analysis Regression coefficient (r) 0.78 0.75
P value  < 0.0001  < 0.0001
Slope 0.98 0.98
Intercept 0.84 0.85
Bland altman analysis Bias (95% CI) 0.71 (0.47 to 0.96) 0.66 (0.39 to 0.91)
Standard deviation 1.92 1.98
Limits of agreement − 3.04 to 4.48 − 3.31 to 4.63
Accuracy Above 95th percentile Sensitivity 0.85 0.88
Specificity 0.98 0.98
PPV 0.85 0.88
NPV 0.91 0.98
Above 75th percentile Sensitivity 0.70 0.85
Specificity 0.94 0.94
PPV 0.85 0.85
NPV 0.87 0.87
Above 40th percentile Sensitivity 0.80 0.80
Specificity 0.91 0.88
PPV 0.90 0.87
NPV 0.82 0.81
Rh incompatibility Linear regression analysis Regression Coefficient (r) 0.73 0.71
P value 0.55 0.08
Slope 0.59 0.55
Intercept 3.80 4.38
Bland altman analysis Bias (95% CI) 0.54 (− 0.10 to 1.18) 0.411 (− 0.25 to 1.07)
Standard deviation 2.29 2.37
Limits of agreement − 3.96 to 2.84 − 3.24 to 2.06
Accuracy Above 95th percentile Sensitivity 0.00 0.16
Specificity 1.00 1.00
PPV 0.00 1.00
NPV 0.88 0.90
Above 75th percentile Sensitivity 0.60 0.60
Specificity 0.92 0.95
PPV 0.66 0.75
NPV 0.90 0.90
Above 40th percentile Sensitivity 0.80 0.65
Specificity 0.93 0.87
PPV 0.88 0.76
NPV 0.87 0.79
G6PD deficiency Linear regression analysis Regression Coefficient (r) 0.84 0.70
P value 0.55 0.08
Slope 0.47 0.50
Intercept 5.48 5.15
Bland altman analysis Bias (95% CI) 0.03 (− 0.61 to 0.69) 0.16 (− 0.73 to 0.40)
Standard deviation 1.87 1.57
Limits of agreement − 3.63 to 3.71 − 3.26 to 2.92
Accuracy Above 95th percentile Sensitivity 0.75 0.75
Specificity 0.90 0.93
PPV 0.50 0.60
NPV 0.96 0.96
Above 75th percentile Sensitivity 0.70 0.60
Specificity 0.91 0.91
PPV 0.77 0.75
NPV 0.88 0.84
Above 40th percentile Sensitivity 0.73 0.86
Specificity 0.73 0.84
PPV 0.68 0.81
NPV 0.77 0.88
Sepsis Linear regression analysis Regression Coefficient (r) 0.87 0.78
P value 0.02 0.19
Slope 0.82 0.65
Intercept 0.93 2.85
Bland altman analysis Bias (95% CI) 0.88 (0.43 to 1.34) 0.80 (0.22 to 1.39)
Standard deviation 1.53 1.96
Limits of agreement − 2.11 to 3.88 − 3.04 to 4.65
Accuracy Above 95th percentile Sensitivity 0.5 0.16
Specificity 1.0 1.0
PPV 1.0 1.0
NPV 0.93 0.88
Above 75th percentile Sensitivity 0.71 0.71
Specificity 1.00 1.00
PPV 1.00 1.00
NPV 0.95 0.95
Above 40th percentile Sensitivity 0.63 0.63
Specificity 0.91 0.94
PPV 0.70 0.70
NPV 0.88 0.89
Birth asphyxia Linear regression analysis Regression Coefficient (r) 0.88 0.80
P value 0.42 0.40
Slope 0.69 0.58
Intercept 2.78 3.94
Bland altman analysis Bias (95% CI) 0.37 (0.01 to 0.74) 0.39 (− 0.01 to 0.79)
Standard deviation 1.76 1.93
Limits of agreement − 3.07 to − 2.44 − 3.40 to 4.18
Accuracy Above 95th percentile Sensitivity 0.73 0.73
Specificity 1.00 0.98
PPV 1.00 0.91
NPV 0.95 0.95
Above 75th percentile Sensitivity 0.87 0.77
Specificity 0.91 0.96
PPV 0.84 0.92
NPV 0.93 0.89
Above 40th percentile Sensitivity 0.88 0.83
Specificity 0.91 0.91
PPV 0.90 0.90
NPV 0.90 0.86