Table 3.
The correlation between bilirubin values obtained from AJO-Neo and TSB along with predictive indices of AJO-Neo in neonates with AAP designated risk factors of hyperbilirubinemia.
Risk factors | Statistical test | Parameters | Right thumb nail plate | Left thumb nail plate | |
---|---|---|---|---|---|
ABO incompatibility | Linear regression analysis | Regression coefficient (r) | 0.78 | 0.75 | |
P value | < 0.0001 | < 0.0001 | |||
Slope | 0.98 | 0.98 | |||
Intercept | 0.84 | 0.85 | |||
Bland altman analysis | Bias (95% CI) | 0.71 (0.47 to 0.96) | 0.66 (0.39 to 0.91) | ||
Standard deviation | 1.92 | 1.98 | |||
Limits of agreement | − 3.04 to 4.48 | − 3.31 to 4.63 | |||
Accuracy | Above 95th percentile | Sensitivity | 0.85 | 0.88 | |
Specificity | 0.98 | 0.98 | |||
PPV | 0.85 | 0.88 | |||
NPV | 0.91 | 0.98 | |||
Above 75th percentile | Sensitivity | 0.70 | 0.85 | ||
Specificity | 0.94 | 0.94 | |||
PPV | 0.85 | 0.85 | |||
NPV | 0.87 | 0.87 | |||
Above 40th percentile | Sensitivity | 0.80 | 0.80 | ||
Specificity | 0.91 | 0.88 | |||
PPV | 0.90 | 0.87 | |||
NPV | 0.82 | 0.81 | |||
Rh incompatibility | Linear regression analysis | Regression Coefficient (r) | 0.73 | 0.71 | |
P value | 0.55 | 0.08 | |||
Slope | 0.59 | 0.55 | |||
Intercept | 3.80 | 4.38 | |||
Bland altman analysis | Bias (95% CI) | 0.54 (− 0.10 to 1.18) | 0.411 (− 0.25 to 1.07) | ||
Standard deviation | 2.29 | 2.37 | |||
Limits of agreement | − 3.96 to 2.84 | − 3.24 to 2.06 | |||
Accuracy | Above 95th percentile | Sensitivity | 0.00 | 0.16 | |
Specificity | 1.00 | 1.00 | |||
PPV | 0.00 | 1.00 | |||
NPV | 0.88 | 0.90 | |||
Above 75th percentile | Sensitivity | 0.60 | 0.60 | ||
Specificity | 0.92 | 0.95 | |||
PPV | 0.66 | 0.75 | |||
NPV | 0.90 | 0.90 | |||
Above 40th percentile | Sensitivity | 0.80 | 0.65 | ||
Specificity | 0.93 | 0.87 | |||
PPV | 0.88 | 0.76 | |||
NPV | 0.87 | 0.79 | |||
G6PD deficiency | Linear regression analysis | Regression Coefficient (r) | 0.84 | 0.70 | |
P value | 0.55 | 0.08 | |||
Slope | 0.47 | 0.50 | |||
Intercept | 5.48 | 5.15 | |||
Bland altman analysis | Bias (95% CI) | 0.03 (− 0.61 to 0.69) | 0.16 (− 0.73 to 0.40) | ||
Standard deviation | 1.87 | 1.57 | |||
Limits of agreement | − 3.63 to 3.71 | − 3.26 to 2.92 | |||
Accuracy | Above 95th percentile | Sensitivity | 0.75 | 0.75 | |
Specificity | 0.90 | 0.93 | |||
PPV | 0.50 | 0.60 | |||
NPV | 0.96 | 0.96 | |||
Above 75th percentile | Sensitivity | 0.70 | 0.60 | ||
Specificity | 0.91 | 0.91 | |||
PPV | 0.77 | 0.75 | |||
NPV | 0.88 | 0.84 | |||
Above 40th percentile | Sensitivity | 0.73 | 0.86 | ||
Specificity | 0.73 | 0.84 | |||
PPV | 0.68 | 0.81 | |||
NPV | 0.77 | 0.88 | |||
Sepsis | Linear regression analysis | Regression Coefficient (r) | 0.87 | 0.78 | |
P value | 0.02 | 0.19 | |||
Slope | 0.82 | 0.65 | |||
Intercept | 0.93 | 2.85 | |||
Bland altman analysis | Bias (95% CI) | 0.88 (0.43 to 1.34) | 0.80 (0.22 to 1.39) | ||
Standard deviation | 1.53 | 1.96 | |||
Limits of agreement | − 2.11 to 3.88 | − 3.04 to 4.65 | |||
Accuracy | Above 95th percentile | Sensitivity | 0.5 | 0.16 | |
Specificity | 1.0 | 1.0 | |||
PPV | 1.0 | 1.0 | |||
NPV | 0.93 | 0.88 | |||
Above 75th percentile | Sensitivity | 0.71 | 0.71 | ||
Specificity | 1.00 | 1.00 | |||
PPV | 1.00 | 1.00 | |||
NPV | 0.95 | 0.95 | |||
Above 40th percentile | Sensitivity | 0.63 | 0.63 | ||
Specificity | 0.91 | 0.94 | |||
PPV | 0.70 | 0.70 | |||
NPV | 0.88 | 0.89 | |||
Birth asphyxia | Linear regression analysis | Regression Coefficient (r) | 0.88 | 0.80 | |
P value | 0.42 | 0.40 | |||
Slope | 0.69 | 0.58 | |||
Intercept | 2.78 | 3.94 | |||
Bland altman analysis | Bias (95% CI) | 0.37 (0.01 to 0.74) | 0.39 (− 0.01 to 0.79) | ||
Standard deviation | 1.76 | 1.93 | |||
Limits of agreement | − 3.07 to − 2.44 | − 3.40 to 4.18 | |||
Accuracy | Above 95th percentile | Sensitivity | 0.73 | 0.73 | |
Specificity | 1.00 | 0.98 | |||
PPV | 1.00 | 0.91 | |||
NPV | 0.95 | 0.95 | |||
Above 75th percentile | Sensitivity | 0.87 | 0.77 | ||
Specificity | 0.91 | 0.96 | |||
PPV | 0.84 | 0.92 | |||
NPV | 0.93 | 0.89 | |||
Above 40th percentile | Sensitivity | 0.88 | 0.83 | ||
Specificity | 0.91 | 0.91 | |||
PPV | 0.90 | 0.90 | |||
NPV | 0.90 | 0.86 |