Table 2.
Coagulation profiles and thromboelastographic parameters between sugammadex 2 mg versus 4 mg.
| 2 mg group | 4 mg group | |||||
|---|---|---|---|---|---|---|
| Before | After | p value | Before | After | p value | |
| PT (s) | 12.8 ± 0.6 | 13.6 ± 0.7 | < 0.001 | 13.0 ± 0.5 | 13.7 ± 0.5 | < 0.001 |
| aPTT (s) | 34.6 ± 3.7 | 34.1 ± 3.5 | 0.410 | 35.5 (34.0 to 38.0) | 35.4 (32.7 to 38.6) | 0.848 |
| PLT (103/µL) | 243 ± 62 | 242 ± 64 | 0.536 | 238 ± 49 | 239 ± 49 | 0.964 |
| R time (min) | 4.5 ± 2.3 | 5.2 ± 2.1 | 0.066 | 4.7 ± 1.8 | 5.8 ± 2.1 | 0.005 |
| K time (min) | 1.5 (1.3 to 1.8) | 1.6 (1.1 to 2.2) | 0.894 | 1.6 (1.2 to 1.9) | 1.5 (1.2 to 1.8) | 0.615 |
| Alpha angle (°) | 63.7 ± 9.3 | 63.5 ± 10.9 | 0.910 | 66.4 (62.0 to 73.2) | 66.8 (64.7 to 71.3) | 0.761 |
| MA (mm) | 67.5 (63.9 to 71.6) | 65.6 (62.1 to 72.0) | 0.585 | 64.8 (60.4 to 72.0) | 65.4 (62.8 to 71.9) | 0.995 |
| LY30 (%) | 0.2 (0.0 to 1.4) | 0.3 (0.0 to 1.1) | 0.790 | 0.3 (0.0 to 1.0) | 0.2 (0.0 to 0.7) | 0.627 |
| CI | 1.5 (− 0.1 to 3.0) | 2.1 (− 0.7 to 3.5) | 0.426 | 1.6 ± 2.4 | 0.8 ± 2.3 | 0.105 |
Data are expressed as mean ± standard deviation or median (25–75% interquartile range).
PT prothrombin time, aPTT activated partial thromboplastin time, PLT platelet, MA maximum amplitude, LY lysis, CI coagulation index.