Table 3.
Uni- and multivariate analysis regarding disease-free survival.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Variable | Hazard ratio for events (95% CI) | P value | Hazard ratio for events (95% CI) | P value |
| Tamoxifen | ||||
| No | 1.00 | 0.019 | 1.00 | 0.008 |
| Yes | 0.46 (0.24–0.88) | 0.38 (0.19–0.78) | ||
| Age at diagnosis (yr) | ||||
| ≤69 | 1.00 | 0.227 | 1.00 | 0.274 |
| >69 | 1.39 (0.82–2.37) | 2.44 (0.75–2.77) | ||
| Tumour size | ||||
| ≤20 mm | 1.00 | 0.165 | 1.00 | 0.327 |
| >20 mm | 1.49 (0.85–2.62) | 1.38 (0.73–2.60) | ||
| Histological grade | ||||
| 1, 2 | 1.00 | 0.001 | 1.00 | 0.005 |
| 3 | 2.55 (1.51–4.33) | 2.61 (1.34–5.05) | ||
| Histological type | ||||
| Invasive ductal carcinoma of no special type | 1.00 | 0.619 | 1.00 | 0.388 |
| Other | 1.30 (0.47–3.59) | 1.61 (0.55–4.71) | ||
| Lymph node status | ||||
| Negative | 1.00 | 0.006 | 1.00 | 0.003 |
| Positive | 2.19 (1.25–3.83) | 2.87 (1.42–5.76) | ||
| Chemotherapy | ||||
| No | 1.00 | 0.727 | 1.00 | 0.729 |
| Yes | 1.10 (0.65–1.86) | 0.88 (0.42–1.83) | ||
| Radiation | ||||
| No | 1.00 | 0.668 | 1.00 | 0.205 |
| Yes | 1.13 (0.66–1.93) | 0.65 (0.34–1.26) | ||