Table 6.
RNA sequencing: selected up- and down-regulated genes in bovine NP cells with FDR < 0.05 and p-value < 0.05 for 5 days of hypo-osmotic versus iso-osmotic treatment.
| Top up-regulated targets | Top down-regulated targets | ||
|---|---|---|---|
| Gene name | Fold change | Gene name | Fold change |
| TRIB3 | 6.01 | IL4R | 0.50 |
| IL11 | 5.18 | TLR4 | 0.47 |
| TNFSF15 | 4.53 | MMP2 | 0.46 |
| TNFRSF21 | 4.30 | SLC4A3 | 0.44 |
| NGF | 4.02 | CD14 | 0.41 |
| SLC7A11 | 3.94 | SLC44A1 | 0.41 |
| HAS2 | 3.79 | SLC6A6 | 0.39 |
| SLC7A5 | 3.74 | MAP4K3 | 0.38 |
| IL6 | 3.61 | SLC37A2 | 0.37 |
| ADAMTS9 | 3.55 | ACAN | 0.36 |
| DDIT4 | 3.13 | CD24 | 0.35 |
| PTGS2 | 3.00 | SLC13A4 | 0.34 |
| COL1A1 | 2.92 | SLC24A3 | 0.29 |
| HSPA5 | 2.91 | SLC46A3 | 0.27 |
| SLC1A4 | 2.76 | AQP1 | 0.26 |
| COL1A2 | 2.74 | ADAMTS12 | 0.22 |
| VEGFC | 2.66 | CXCL5 | 0.21 |
| SLC1A5 | 2.56 | TNFRSF11B | 0.21 |
| SLC3A2 | 2.49 | SLC39A8 | 0.20 |
| VGF | 2.15 | SLC4A11 | 0.02 |