Table 2.
Univariate and multivariate analysis of factors associated with overall (A) and disease-free (B) survival in plasmatic validating set (log-rank test and Cox model).
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| p Value | Hazard ratio | [95% CI] | p Value | |
| (A) | ||||
| Age | 0.127 | — | ||
| Gender | 0.247 | — | ||
| TNM score T1–T2 versus T3–T4 | 0.162 | — | ||
| Positive lymph nodes | 0.815 | — | ||
| Size ≥2 cm | 0.934 | — | ||
| Differentiation | 0.715 | — | ||
| Positive margin | 0.800 | — | ||
| Lymphovascular invasion | 0.558 | — | ||
| Perineural invasion | 0.826 | — | ||
| Chronic pancreatitis | 0.115 | — | ||
| Adjuvant chemotherapy | 0.952 | — | ||
| High SFN plasmatic level | 0.308 | — | ||
| (B) | ||||
| Age | 0.161 | 0.955 | [0.90; 1.003] | 0.068 |
| Gender | 0.421 | — | ||
| TNM score T1–T2 versus T3–T4 | 0.593 | — | ||
| Positive lymph nodes | 0.591 | — | ||
| Size ≥2 cm | 0.659 | — | ||
| Differentiation | 0.662 | — | ||
| Positive margin | 0.865 | — | ||
| Lymphovascular invasion | 0.105 | 1.94 | [0.83; 4.51] | 0.123 |
| Perineural invasion | 0.790 | — | ||
| Chronic pancreatitis | 0.508 | — | ||
| Adjuvant chemotherapy | 0.369 | — | ||
| High SFN plasmatic level | 0.019 | 2.380 | [1.02; 5.531] | 0.006 |
Bold values indicate statistical significance p < 0.05.