Table 3.
The distinguished different metabolites between the low and high dosage tramadol groups.
| No. | Name_des | Pvalue | ROC | VIP | Up. Down |
|---|---|---|---|---|---|
| 1 | Glutamine | 0.01263 | 0.916667 | 1.61973 | Down |
| 2 | Phosphatidyl ethanolamine | 0.001618 | 1 | 1.519291 | Down |
| 3 | Fructose | 0.030563 | 0.833333 | 1.211801 | Down |
| 4 | Dehydroascorbic Acid | 0.012467 | 1 | 1.282237 | Down |
| 5 | Glucose | 0.015118 | 0.944444 | 1.031273 | Down |
| 6 | Galactose | 0.01019 | 0.944444 | 1.263042 | Down |
| 7 | Lysine | 0.015042 | 0.888889 | 1.166203 | Down |
| 8 | Mannitol | 0.000155 | 0.972222 | 1.893367 | Down |
| 9 | N-alpha-Acetyl-L-ornithine | 0.014213 | 0.888889 | 1.254009 | Down |
| 10 | Lipoic acid | 0.012495 | 0.888889 | 1.235809 | Down |
| 11 | Pantothenic acid | 0.002624 | 0.944444 | 1.539796 | Down |
| 12 | Gluconic acid | 0.002237 | 0.972222 | 1.232332 | Down |
| 13 | Fructose 2,6-biphosphate | 0.000463 | 0.972222 | 1.722629 | Down |
| 14 | 5-Hydroxyindole-acetic acid | 0.005185 | 0.944444 | 1.341267 | Down |
| 15 | Oleic acid | 0.000283 | 1 | 2.473685 | Down |
| 16 | Stearic acid | 0.004576 | 0.944444 | 1.370856 | Down |
| 17 | Spermidine | 0.005586 | 0.916667 | 1.269467 | Down |
| 18 | Fructose-6-phosphate | 0.001791 | 1 | 2.264901 | Down |
| 19 | 6-Phosphate gluconic acid | 0.017809 | 0.888889 | 1.170693 | Down |
| 20 | Pelargonic acid | 0.000378 | 1 | 1.08774 | Down |
| 21 | Thymine | 0.034584 | 0.833333 | 1.092957 | Down |
| 22 | Oxalic acid | 5.98E-05 | 1 | 1.503521 | Up |
| 23 | Azelaic acid | 0.040329 | 0.833333 | 1.63793 | Up |
| 24 | Sucrose | 7.84E-05 | 1 | 3.291901 | Up |
| 25 | Prostaglandin A2 | 0.005454 | 0.944444 | 1.511029 | Up |
| 26 | Caprylic acid | 0.037437 | 0.916667 | 1.059006 | Up |
| 27 | Capric Acid | 0.002148 | 1 | 1.303616 | Up |
| 28 | γ-Hydroxybutyric acid | 0.00391 | 1 | 1.01887 | Up |
| 29 | N-Acetyl-L-leucine | 0.006074 | 0.972222 | 3.048863 | Up |