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. 2020 Jul 7;10:11143. doi: 10.1038/s41598-020-68113-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Characterization of Gprc6a-^KGKY-knockin mice. Comparison of the fasting blood glucose (a), serum insulin (b) and serum FGF-21 levels (c), serum levels of cholesterol (d), triglyceride (e) and free fatty acid (f) in wild type and Gprc6a-^KGKY-knokin male mice at age of 10 week-old. Values represent the mean ± SEM. *Significant difference between wild type and Gprc6a-^KGKY-knockin mice (P < 0.05, Student’s t test; n = 6).