Table 4.
Multivariate Conditional Logistic Regression of Physical Comorbidity Within the 1 year Prior to the Index Date Among Patients with Newly Diagnosed Schizophrenia and Controls (Ratio 1:4), From 2000 to 2013
| Cases (N = 1969) | Controls (N = 7876) | ||||
|---|---|---|---|---|---|
| Characteristic N (%) | N (%) | N (%) | Adjusted Risk Ratioa | 95% CI | P value |
| Physical illness | |||||
| Hypertension | 50 (2.5) | 87 (1.1) | 1.93 | 1.33–2.82 | .001* |
| Other forms of heart diseaseb | 50 (2.5) | 84 (1.1) | 2.07 | 1.44–2.98 | <.001* |
| Cerebrovascular disease | 19 (1.0) | 20 (0.3) | 2.96 | 1.55–5.65 | .001* |
| COPDc | 75 (3.8) | 181 (2.3) | 1.50 | 1.13–2.00 | .005* |
| Asthma | 44 (2.2) | 89 (1.1) | 1.76 | 1.21–2.55 | .003* |
| Irritable bowel syndrome | 50 (2.5) | 96 (1.2) | 2.00 | 1.41–2.84 | <.001* |
aVariables regarding physical comorbidity (table 3) were included for multivariate logistic regression; variables with a strongly significant association (P < .01) were retained in the final model.
bICD-9 codes: 420.xx-429.xx.
cChronic obstructive pulmonary disease.
*P < .01.