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. 2016 Sep;37(9):774–778. [Article in Chinese] doi: 10.3760/cma.j.issn.0253-2727.2016.09.009

表2. 免疫球蛋白重链可变区(IGHV)突变患者与未突变患者临床特征比较.

IGHV突变组(30例) IGHV未突变组(10例) P
血常规
 WBC[×109/L,M(范围)] 16.79(2.42~126.82) 19.12(2.28~61.68) 0.749
 HGB[g/L,M(范围)] 107(53~151) 102(85~142) 0.753
 PLT[×109/L,M(范围)] 92(34~569) 125(38~440) 0.368
 ALC[×109/L,M(范围)] 10.54(0.44~123.00) 7.08(0.28~45.50) 0.480
肿瘤负荷
 LDH[U/L,M(范围)] 173(107~515) 225(118~400) 0.965
 β2微球蛋白[mg/L,M(范围)] 4.18(1.54~11.90) 3.50(2.41~9.69) 0.971
免疫球蛋白
 IgG[g/L,M(范围)] 10.70(5.28~23.50) 12.90(7.71~23.50) 0.038
 IgA[g/L,M(范围)] 1.06(0.21~3.13) 1.66(0.81~2.93) 0.040
 IgM[g/L,M(范围)] 0.90(0.18~31.10) 1.22(0.35~16.50) 0.659
细胞遗传学
 RB-1缺失[例(%)] 0 0 -
 17P缺失[例(%)] 0 2(6.67) 0.060
 ATM缺失[例(%)] 0 0 -
 IgH易位[例(%)] 5(16.67) 1(3.33) 1.000

注:ALC:淋巴细胞绝对计数;-:无法统计