Table 2.

Significant Clusters of the Between-Group Contrasts of the Free-Water in Gray Matter Surface.

P-FWE Value	Cluster Size (vortex)	Hemisphere	Overlap with Desikan–Killiany DK40 Atlas Regions.
Baseline SSD > HC
.005	3457	Right	28% inferior parietal, 22% supra marginal, 14% middle temporal, 11% superior parietal, 9% inferior temporal, 8% banks of the superior temporal sulcus
.031	1085	Right	47% precuneus, 22% paracentral, 20% posterior cingulate, 7% isthmus cingulate
.025	703	Right	48% inferior temporal, 34% middle temporal, 12% superior temporal
.037	443	Right	76% lateral orbitofrontal, 23% pars orbitalis
.024	258	Right	64% fusiform, 32% parahippocampal
.026	1347	Left	42% middle temporal, 30% inferior temporal, 11% fusiform, 11% banks of the superior temporal sulcus
.037	201	Left	73% fusiform, 20% parahippocampal
Baseline non-SSD > HC
.037	598	Left	50% lateral occipital, 19% middle temporal, 14% banks of the superior temporal sulcus, 12% inferior temporal
.038	348	Left	53% inferior temporal, 41% middle temporal
.013	3691	Right	19% interior temporal, 17% lateral occipital, 16% fusiform, 13% middle temporal, 11% lingual, 8 % inferior parietal
Decrease after 2 years, SSD > HC
.003	7275	Left	16% superior parietal, 13% inferior parietal, 12% lateral occipital, 9% middle temporal, 8% supramarginal, 6% postcentral, 4% pericalcarine, 4% inferior temporal, 4% precuneus, 4% precentral, 3% lingual, 3% ishmus cingulate, 3% banks of the superior temporal sulcus, 3% cuneus, 3% pars opercularis
.013	2146	Right	22% superior parietal, 18% precuneus, 17% lateral occipital, 14% inferior parietal, 12% cuneus, 9 % pericalcarine, 8 % lingual
.034	328	Right	81% supramarginal, 17% inferior parietal
.046	139	Right	100% inferior parietal
Decrease after 2 years, non-SSD > HC
–	–	–	–

Note: Results obtained using log-transformation, threshold-free-cluster-enhancement, and thresholded using P-FWE < .05.