表1. 接受allo-HSCT的206例AML患者初诊时突变基因的检出情况.
| 基因突变 | 例数(%) |
| FLT3-ITD | 26(12.6) |
| duCEBPA | 20(9.7) |
| DNMT3A R882+FLT3-ITD+NPM1 | 14(6.8) |
| DNMT3A R882 | 14(6.8) |
| siCEBPA | 9(4.4) |
| FLT3-ITD+NPM1 | 7(3.4) |
| FLT3-ITD+duCEBPA | 4(1.9) |
| FLT3-TKD | 4(1.9) |
| DNMT3A R882+FLT3-ITD | 4(1.9) |
| c-kit | 3(1.5) |
| NPM1 | 3(1.5) |
| duCEBPA+c-kit | 2(1.0) |
| DNMT3A R882+NPM1 | 2(1.0) |
| siCEBPA+NPM1 | 2(1.0) |
| DNMT3A R882+NPM1+ FLT3-TKD | 2(1.0) |
| FLT3-ITD+siCEBPA | 1(0.5) |
| duCEBPA+ FLT3-TKD | 1(0.5) |
| NPM1+ c-kit | 1(0.5) |
| DNMT3A R882+ FLT3-TKD | 1(0.5) |
| FLT3-TKD+ NPM1 | 1(0.5) |
| DNMT3A R882+NPM1+siCEBPA | 1(0.5) |
| DNMT3A R882+FLT3-ITD+NMP1+c-kit | 1(0.5) |
| DNMT3AR882+NPM1+siCEBPA+FLT3-TKD | 1(0.5) |
| 阴性组 | 82(39.8) |
注:duCEBPA:双突变CEBPA;siCEBPA:单突变CEBPA;阴性组:未检出任何已知突变