Figure 2.

IC₅₀ values of doxorubicin are different between the passages of DFs and ADSCs. The IC₅₀ values of DFs were significantly decreased as the passages of DFs increased, while the values slightly changed when the passage of ADSCs increased from the 3rd to the 6th passage, and from the 6th to the 9th or 12th passage (A). The IC₅₀ values of doxorubicin are nonsignificant between DFs and ADSCs at the 3rd passage; however, these values are significantly different between DFs and ADSCs at the 6th, 9th and 12th passages (B).

Abbreviations: ADSCs, adipose-derived stem cells; DFs, dermal fibroblasts; IC₅₀, the half maximal inhibitory concentration.