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Common reasons that participants convey for not participating in clinical trials[6,7,8,10,11,12,13,14,15]
| Intricacy of study protocol |
| Sociocultural issues |
| Negative publicity by media |
| Inconvenient study schedules |
| Geographical distance |
| Concerns about getting a placebo |
| Concern about benefits of investigational product |
| Discouragement by treating physician |
| Lack of awareness about clinical trials |
| Fear of adverse events |
