Table 2.
Univariate Cox Regression Analysis for Disease-Free Survival and Overall Survival in 250 Patients with Colorectal Cancer
Factors | Disease-Free Survival | Overall Survival | ||
---|---|---|---|---|
HR (95% CI) | p value* | HR (95% CI) | p value* | |
Gender (male/female) | 1.222 (0.766–1.949) | 0.399 | 1.193 (0.745–1.909) | 0.463 |
Age, years (≤58>58) | 0.984 (0.618–1.567) | 0.945 | 0.998 (0.624–1.594) | 0.992 |
Tobacco history (No/Yes) | 1.088 (0.654–1.812) | 0.745 | 1.112 (0.667–1.853) | 0.685 |
Alcohol history (No/Yes) | 1.070 (0.548–2.089) | 0.843 | 1.114 (0.570–2.176) | 0.751 |
Family history of cancer (No/Yes) | 0.979 (0.501–1.194) | 0.951 | 1.036 (0.529–2.026) | 0.919 |
Hypertension (No/Yes) | 0.766 (0.381–1.542) | 0.445 | 0.877 (0.449–1.173) | 0.700 |
Diabetes (No/Yes) | 1.670 (0.723–3.858) | 0.230 | 1.667 (0.722–3.852) | 0.231 |
Tumor status (1–2/3-4) | 16.61 (2.308–119.625) | 0.005* | 8.275 (2.028–33.770) | 0.003* |
Nodal status (0/1) | 2.972 (1.864–4.738) | <0.001* | 2.899 (1.805–4.622) | <0.001* |
Metastasis status (0/1) | 4.796 (3.002–7.633) | <0.001* | 4.602 (2.871–7.377) | <0.001* |
TNM stages (I–II/III–IV) | 12.13 (5.250–28.025) | <0.001* | 11.688 (5.507–27.015) | <0.001* |
PT (≥11.85/<11.85) | 3.457 (2.153–5.550) | <0.001* | 3.614 (2.252–5.801) | <0.001* |
PTA% (≥91.75/<91.75) | 0.418 (0.252–0.691) | 0.001 | 0.424 (0.256–0.703) | 0.001 |
INR (≥1.15/<1.15) | 3.225 (1.765–5.895) | <0.001* | 3.472 (1.930–6.246) | <0.001* |
APTT (≥25.85/<25.85) | 2.281 (1.394–3.731) | 0.001* | 2.687 (1.611–4.483) | <0.001* |
Fibrinogen (≥3.245/<3.245) | 1.622 (1.043–2.646) | 0.032 | 1.653 (1.035–2.641) | 0.036 |
TT (≥20.70/<20.70) | 1.562 (0.716–0.341) | 0.263 | 1.575 (0.721–3.439) | 0.254 |
PLT (≥239.5/<239.5) | 1.633 (1.003–2.659) | 0.051 | 1.414 (0.874–2.289) | 0.158 |
PLR (≥113/<113) | 1.699 (0.985–2.931) | 0.057 | 1.707 (0.988–2.948) | 0.055 |
Notes: *Univariate analysis, p<0.05 considered as statistically significant. Bold values indicate significant differences (p<0.05).
Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.