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. 2020 Jul 3;12:5373–5384. doi: 10.2147/CMAR.S246695

Table 2.

Univariate Cox Regression Analysis for Disease-Free Survival and Overall Survival in 250 Patients with Colorectal Cancer

Factors Disease-Free Survival Overall Survival
HR (95% CI) p value* HR (95% CI) p value*
Gender (male/female) 1.222 (0.766–1.949) 0.399 1.193 (0.745–1.909) 0.463
Age, years (≤58>58) 0.984 (0.618–1.567) 0.945 0.998 (0.624–1.594) 0.992
Tobacco history (No/Yes) 1.088 (0.654–1.812) 0.745 1.112 (0.667–1.853) 0.685
Alcohol history (No/Yes) 1.070 (0.548–2.089) 0.843 1.114 (0.570–2.176) 0.751
Family history of cancer (No/Yes) 0.979 (0.501–1.194) 0.951 1.036 (0.529–2.026) 0.919
Hypertension (No/Yes) 0.766 (0.381–1.542) 0.445 0.877 (0.449–1.173) 0.700
Diabetes (No/Yes) 1.670 (0.723–3.858) 0.230 1.667 (0.722–3.852) 0.231
Tumor status (1–2/3-4) 16.61 (2.308–119.625) 0.005* 8.275 (2.028–33.770) 0.003*
Nodal status (0/1) 2.972 (1.864–4.738) <0.001* 2.899 (1.805–4.622) <0.001*
Metastasis status (0/1) 4.796 (3.002–7.633) <0.001* 4.602 (2.871–7.377) <0.001*
TNM stages (I–II/III–IV) 12.13 (5.250–28.025) <0.001* 11.688 (5.507–27.015) <0.001*
PT (≥11.85/<11.85) 3.457 (2.153–5.550) <0.001* 3.614 (2.252–5.801) <0.001*
PTA% (≥91.75/<91.75) 0.418 (0.252–0.691) 0.001 0.424 (0.256–0.703) 0.001
INR (≥1.15/<1.15) 3.225 (1.765–5.895) <0.001* 3.472 (1.930–6.246) <0.001*
APTT (≥25.85/<25.85) 2.281 (1.394–3.731) 0.001* 2.687 (1.611–4.483) <0.001*
Fibrinogen (≥3.245/<3.245) 1.622 (1.043–2.646) 0.032 1.653 (1.035–2.641) 0.036
TT (≥20.70/<20.70) 1.562 (0.716–0.341) 0.263 1.575 (0.721–3.439) 0.254
PLT (≥239.5/<239.5) 1.633 (1.003–2.659) 0.051 1.414 (0.874–2.289) 0.158
PLR (≥113/<113) 1.699 (0.985–2.931) 0.057 1.707 (0.988–2.948) 0.055

Notes: *Univariate analysis, p<0.05 considered as statistically significant. Bold values indicate significant differences (p<0.05).

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.