Table 3.
Bivariate Logistic Regression of TILs PD-L1 and PD-1 Expression
| PD-L1 Positive/Negative | R2 | PD-1 ± Positive/Negative | R2 | |||||
|---|---|---|---|---|---|---|---|---|
| HR | 0.95 | p value | HR | 0.95 | p value | |||
| CD3± | 7.894 | 3.004–20.745 | <0.001* | 0.25 | 6.303 | 2.548–15.589 | <0.001* | 0.217 |
| CD4± | 7.544 | 3.05–18.659 | <0.001* | 0.257# | 5.769 | 2.40–13.869 | <0.001* | 0.205 |
| CD8± | 8.28 | 3.243–21.138 | <0.001* | 0.271# | 5.263 | 2.148–12.894 | <0.001* | 0.182 |
| FOXP3± | 17.182 | 6.196–47.646 | <0.001* | 0.423# | 10.015 | 3.869–25.923 | <0.001* | 0.314# |
| PD-1± | 4.739 | 2.003–11.217 | <0.001* | 0.166 | ||||
Notes: *p<0.05; #R2>0.25.
Abbreviations: −, negative; +, positive; PD-1, programed death-1; PD-L1, programed death-ligand 1; TILs, tumor-infiltrating lymphocytes; R2, Nagelkerke’s R2.