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. 2020 Jul 3;13:6497–6509. doi: 10.2147/OTT.S256818

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© 2020 Wei et al.

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Comparison of transcriptomic profiles of TNBCs between the metastasis and non-metastasis group. (A and B) Volcano plots of transcripts of TNBCs of metastasis group relative to non-metastasis group at diagnosis (A) or post-NACT (B). Red and blue dots represent up-regulated and down-regulated genes with |log2(fold change)|≥1.0 and p values <0.05, respectively. (C and D) Heat maps with clusters of differentially expressed genes with |log2(fold change)|≥1.0 and p values <0.05 at diagnosis (C) and post-NACT (D).

Abbreviations: M, metastasis; N, non-metastasis; TNBC, triple-negative breast cancer; NACT, neoadjuvant chemotherapy.