Table 1.
Characteristics of TNBC Patients and Tumors
| Patients Characteristics | Total (n=10) | Metastasis (n=2) | Non-Metastasis (n=8) | P value * |
|---|---|---|---|---|
| Age, years (median(range)) | 50 (40, 62) | 53.5 (46, 61) | 50 (40, 62) | P>0.05 |
| Sex | ||||
| Female | 10 | 2 | 8 | |
| Menstruation status | ||||
| Premenopausal | 5 | 1 | 4 | |
| Postmenopausal | 5 | 1 | 4 | |
| BMI | 27.2±3.82 | 24.9±7.21 | 27.8±3.07 | P>0.05 |
| <25 | 2 | 1 | 1 | |
| ≥25, <30 | 5 | 0 | 5 | |
| ≥30 | 3 | 1 | 2 | |
| Clinical T stage | ||||
| T2 | 6 | 1 | 5 | |
| T3 | 2 | 0 | 2 | |
| T4 | 2 | 1 | 1 | |
| Clinical N stage | ||||
| N0 | 4 | 1 | 3 | |
| N1 | 4 | 1 | 3 | |
| N3 | 2 | 0 | 2 | |
| Clinical M stage | ||||
| M0 | 10 | 2 | 8 | |
| AJCC stage | ||||
| II | 5 | 1 | 4 | |
| III | 5 | 1 | 4 | |
| Pre-NACT Ki-76 (Mean±SD) | 51±28.1 | 40±42.4 | 53±26.9 | P>0.05 |
| Low (<11%) | 2 | 1 | 1 | |
| Intermediate (11–20%) | 1 | 0 | 1 | |
| High (>20%) | 7 | 1 | 6 | |
| Post-NACT Ki-76 (Mean±SD) | 41±39.5 | 36±48.8 | 43±40.6 | P>0.05 |
| Low (<11%) | 4 | 1 | 3 | |
| Intermediate (11–20%) | 1 | 0 | 1 | |
| High (>20%) | 5 | 1 | 4 | |
| Response evaluation criteria in RECIST | ||||
| PR | 5 | 2 | 3 | |
| SD | 4 | 0 | 4 | |
| PD | 1 | 0 | 1 | |
| Surgery | ||||
| BCS | 3 | 2 | 1 | |
| Mastectomy | 7 | 0 | 7 | |
| Modified radical mastectomy | 0 | 0 | 0 | |
| Follow-up (month, median, range) | 25(14, 67) | 15.5(14, 17) | 27.5(23, 67) |
Note: *Mann–Whitney U-test.
Abbreviations: BMI, body mass index; BCS, breast conserving surgery; TNBC, triple-negative breast cancer; NACT, neoadjuvant chemotherapy.