Table 1.
Behavior cohorts
| Cohort 1 | Male | Female | ||||
|---|---|---|---|---|---|---|
| Behavior | WT | Gtf2i * | CD | WT | Gtf2i* | CD |
| Pup USV P3 and P5 | 11 | 12 | 8 | 12 | 12 | 9 |
| Sensorimotor battery | 12 | 15 | 7 | 13 | 11 | 11 |
| Elevated plus maze | 12 | 13 | 7 | 12 | 12 | 10 |
| 1 H locomotor activity | 12 | 14 | 8 | 13 | 12 | 10 |
| Marble burying | 12 | 14 | 8 | 13 | 12 | 10 |
| Rotarod | 12 | 14 | 8 | 13 | 12 | 10 |
| Three-chamber social approach | 10 | 12 | 6 | 10 | 8 | 10 |
| Resident intruder | 12 | 14 | 8 | NA | NA | NA |
| Cohort 2 | Male | Female | ||||
| Behavior | WT | Gtf2i * | CD | WT | Gtf2i * | CD |
| Modified three-chamber social approach | 10 | 3 | 9 | 11 | 14 | 12 |
| Tube test of social dominance | 11 | 3 | 9 | 11 | 14 | 12 |
| PPI | 10 | 3 | 9 | 11 | 14 | 12 |
| Conditioned fear | 9 | 3 | 8 | 10 | 14 | 12 |
| Shock sensitivity | 10 | 3 | 9 | 11 | 14 | 12 |