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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: J Glaucoma. 2019 Nov;28(11):945–951. doi: 10.1097/IJG.0000000000001380

Table 3.

Conclusions in Abstract of the 4 commonly cited articles.

Ref # From Abstract Conclusions Comment on Results
A “Definite loss of axons occurs prior to reproducible visual field defects in some patients suspected of having glaucoma.” Two eyes showed results consistent with this conclusion. The more extreme had a normal Goldmann VF, but 40% loss of axons
B “Throughout the central 30 degrees of the retina, 20% of the normal number of cells were gone in locations with 5-dB sensitivity loss,…” First, only 3 post-mortem eyes were involved. Second, the data supply weak support for the conclusion. Third, based upon a linear model, the data suggest VF sensitivity is lost before RGCs are missing.
C “At least 25% to 35% RGC loss is associated with statistical abnormalities in automated visual field testing.” First, the data supply weak support for the conclusion. Second, based upon a linear model, the data suggest VF sensitivity is lost before RGCs are missing.
D “Current perimetry regimens with either white or monochromatic stimuli do not provide a useful estimate of ganglion cell loss until a substantial proportion have died.” First, the data support the conclusion. Second, based upon a linear model, the data suggest VF sensitivity is lost before RGCs are missing.