Table 3.
Conclusions in Abstract of the 4 commonly cited articles.
| Ref # | From Abstract Conclusions | Comment on Results |
|---|---|---|
| A | “Definite loss of axons occurs prior to reproducible visual field defects in some patients suspected of having glaucoma.” | Two eyes showed results consistent with this conclusion. The more extreme had a normal Goldmann VF, but 40% loss of axons |
| B | “Throughout the central 30 degrees of the retina, 20% of the normal number of cells were gone in locations with 5-dB sensitivity loss,…” | First, only 3 post-mortem eyes were involved. Second, the data supply weak support for the conclusion. Third, based upon a linear model, the data suggest VF sensitivity is lost before RGCs are missing. |
| C | “At least 25% to 35% RGC loss is associated with statistical abnormalities in automated visual field testing.” | First, the data supply weak support for the conclusion. Second, based upon a linear model, the data suggest VF sensitivity is lost before RGCs are missing. |
| D | “Current perimetry regimens with either white or monochromatic stimuli do not provide a useful estimate of ganglion cell loss until a substantial proportion have died.” | First, the data support the conclusion. Second, based upon a linear model, the data suggest VF sensitivity is lost before RGCs are missing. |