FIG 2.

PTCs have reduced viral burden prior to ART initiation. (A) Plasma viral load levels at peak infection and pre-ART time points. (B) Total SIV DNA levels in purified blood CD4 T cells pre-ART. (C) Cell associated SIV DNA and RNA levels in total rectal biopsy samples pre-ART. (D) Gating strategy for CD4 T cell subsets from LN. (E) SIV DNA levels in sorted CD4 T cell subsets from peripheral blood (E) and lymph node (F) at a pre-ART time point. (G and H) Expression of CD8 T cell functional markers (GzmB, granzyme B; Perf, perforin) on total CD8 T cells in peripheral blood (G) and LN (H). Lines designate mean values.