TABLE 1.
Glycoprotein content in fibroblast-derived cell-free virions
| gO GT mutant | Mean amount or protein (range [%])a
|
||
|---|---|---|---|
| gB | gH | gO | |
| GT1c | 121 (83–208) | 124 (63–200) | 72 (42–100) |
| GT2b | 136 (111–167) | 170 (91–205) | ND |
| GT3 | 142 (109–169) | 235 (179–303) | 59 (16–91) |
| GT3/1c | 116 (83–147) | 121 (100–143) | 28 (16–40) |
| GT1c/3 | 150 (111–189) | 84 (53–143) | 17 (6–27) |
| GT4 | 73 (67–80) | 119 (105–133)b | 98 (71–125)b |
| GT5 | 130 (74–172) | 102 (53–222) | 100 (45–200) |
| GT1c_C343S2 | 34 (22–67) | 40 (29–59)b | 29 (18–59)b |
a
Glycoprotein levels were normalized to the level of the major capsid protein. The data shown are the results of two to four independent experiments. ND, not detectable.
b
Data have been previously published (24).