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. 2020 Jul 1;94(14):e00542-20. doi: 10.1128/JVI.00542-20

TABLE 1.

Surface plasmon resonance analysis of HAdV hexon interactions with hLF and hLfcin1-49

Ligand Analyte Parametera
KD ka (M−1 · s−1) kd (s−1)
HAdV-C5 hexon hLF 29 ± 3.6 nM 5.3 × 104 ± 2.6 × 103 0.00154 ± 0.00024
HAdV-B35 hexon hLF 151 ± 14 nM 2.5 × 104 ± 2.5 × 103 0.00354 ± 0.00014
HAdV-A31 hexon hLF 827 ± 55 nM 1.2 × 104 ± 1.1 × 103 0.01011 ± 0.00024
HAdV-C5 hexon hLfcin1-49 0.73 ± 0.206 μM ND ND
HAdV-B35 hexon hLfcin1-49 22.1 ± 13.6 μM ND ND
HAdV-A31 hexon hLfcin1-49 187 ± 155 μM ND ND
a

Data are shown as averages from three independent measurements. KD, equilibrium dissociation rate constant; ka, association rate constant; kd, dissociation rate constant; ND, not determined due to very fast kinetics and likely large errors in determining kinetics.