TABLE 2.
Significance analysis of RNA copy numbers from pA/BV-, BVΔERNS_comp-, and BVΔE1-infected SK-6 or SK-6-BV-ERNS cellsa
| Cell type or supernatant and comparison | Significant? | Summaryb | Adjusted P value |
|---|---|---|---|
| SK-6-BV-ERNS supernatant | |||
| 2h BVΔERNS vs 2h pA/BV | No | NS | >0.9999 |
| 2h BVΔERNS vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔERNS vs 48h BVΔERNS | Yes | * | 0.0187 |
| 2h BVΔERNS vs 48h pA/BV | Yes | * | 0.0202 |
| 2h BVΔERNS vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 48h BVΔERNS | Yes | * | 0.0187 |
| 2h pA/BV vs 48h pA/BV | Yes | * | 0.0202 |
| 2h pA/BV vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔE1 vs 48h BVΔERNS | Yes | * | 0.0187 |
| 2h BVΔE1 vs 48h pA/BV | Yes | * | 0.0202 |
| 2h BVΔE1 vs 48h BVΔE1 | No | NS | >0.9999 |
| 48h BVΔERNS vs 48h pA/BV | No | NS | 0.9611 |
| 48h BVΔERNS vs 48h BVΔE1 | Yes | * | 0.0187 |
| 48h pA/BV vs 48h BVΔE1 |
Yes | * | 0.0202 |
| SK-6-BV-ERNS cells | |||
| 2h BVΔERNS vs 2h pA/BV | No | NS | >0.9999 |
| 2h BVΔERNS vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔERNS vs 48h BVΔERNS | Yes | * | 0.0155 |
| 2h BVΔERNS vs 48h pA/BV | Yes | *** | 0.0001 |
| 2h BVΔERNS vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 48h BVΔERNS | Yes | * | 0.0155 |
| 2h pA/BV vs 48h pA/BV | Yes | *** | 0.0001 |
| 2h pA/BV vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔE1 vs 48h BVΔERNS | Yes | * | 0.0155 |
| 2h BVΔE1 vs 48h pA/BV | Yes | *** | 0.0001 |
| 2h BVΔE1 vs 48h BVΔE1 | No | NS | >0.9999 |
| 48h BVΔERNS vs 48h pA/BV | No | NS | 0.0594 |
| 48h BVΔERNS vs 48h BVΔE1 | Yes | * | 0.0155 |
| 48h pA/BV vs 48h BVΔE1 |
Yes | *** | 0.0001 |
| SK-6 supernatant | |||
| 2h BVΔERNS vs 2h pA/BV | No | NS | >0.9999 |
| 2h BVΔERNS vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔERNS vs 48h BVΔERNS | No | NS | >0.9999 |
| 2h BVΔERNS vs 48h pA/BV | Yes | ** | 0.0028 |
| 2h BVΔERNS vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 48h BVΔERNS | No | NS | >0.9999 |
| 2h pA/BV vs 48h pA/BV | Yes | ** | 0.0028 |
| 2h pA/BV vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔE1 vs 48h BVΔERNS | No | NS | >0.9999 |
| 2h BVΔE1 vs 48h pA/BV | Yes | ** | 0.0065 |
| 2h BVΔE1 vs 48h BVΔE1 | No | NS | >0.9999 |
| 48h BVΔERNS vs 48h pA/BV | Yes | ** | 0.0028 |
| 48h BVΔERNS vs 48h BVΔE1 | No | NS | >0.9999 |
| 48h pA/BV vs 48h BVΔE1 |
Yes | ** | 0.0028 |
| SK-6 cells | |||
| 2h BVΔERNS vs 2h pA/BV | No | NS | >0.9999 |
| 2h BVΔERNS vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔERNS vs 48h BVΔERNS | No | NS | >0.9999 |
| 2h BVΔERNS vs 48h pA/BV | Yes | * | 0.043 |
| 2h BVΔERNS vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 2h BVΔE1 | No | NS | >0.9999 |
| 2h pA/BV vs 48h BVΔERNS | No | NS | >0.9999 |
| 2h pA/BV vs 48h pA/BV | Yes | * | 0.043 |
| 2h pA/BV vs 48h BVΔE1 | No | NS | >0.9999 |
| 2h BVΔE1 vs 48h BVΔERNS | No | NS | >0.9999 |
| 2h BVΔE1 vs 48h pA/BV | Yes | * | 0.043 |
| 2h BVΔE1 vs 48h BVΔE1 | No | NS | >0.9999 |
| 48h BVΔERNS vs 48h pA/BV | Yes | * | 0.0468 |
| 48h BVΔERNS vs 48h BVΔE1 | No | NS | >0.9999 |
| 48h pA/BV vs 48h BVΔE1 | Yes | * | 0.043 |
a
One-way ANOVA followed by Tukey`s multiple-comparison test was performed using GraphPad Prism version 8.0.1 for Windows (GraphPad Software, San Diego, CA, USA).
b
*, <0.05; **, <0.01; ***, <0.001; NS, not significant.