Table 4: Differentially regulated genes in females.
Genes that were differentially regulated between the dieldrin exposed group vs the control group in female mice (n =8 per treatment group, p < 0.05). One star(*) indicates the genesth at do not cluster with other genes in STRING network analysis; two stars (**) indicates that the gene was not mapped to the STRING database.
| Gene | p-value | Fold change (2−ΔΔCt) | Expression in exposed group |
|---|---|---|---|
| Csf1 | 0.0003 | 1.5955447 | Unregulated |
| Tfrc | 0.0024 | 1.2815964 | Upregulated |
| Agtr2 | 0.0054 | 1.9362228 | Upregulated |
| Stat4 | 0.0055 | 1.7925272 | Upregulated |
| Cd68 | 0.0060 | 0.6350103 | Downregulated |
| Socs1 | 0.0075 | 0.7602232 | Downregulated |
| Ptprc | 0.0078 | 1.3596591 | Upregulated |
| Ikbkb | 0.0140 | 0.7839894 | Downregulated |
| Nfkb2 | 0.0198 | 1.2670066 | Upregulated |
| Col4a5** | 0.0222 | 1.4464285 | Upregulated |
| Nfkb1 | 0.0238 | 1.2724289 | Upregulated |
| CxcllO | 0.0337 | 2.0286149 | Upregulated |
| Il1A | 0.0351 | 0.8374558 | Downregulated |
| Cd28 | 0.0382 | 0.4077085 | Downregulated |
| Stat3 | 0.0419 | 1.1916636 | Upregulated |
| Il5 | 0.0437 | 2.6215317 | Upregulated |
| Socs2 | 0.0465 | 1.2408090 | Upregulated |
| Ski* | 0.0482 | 1.2297090 | Upregulated |