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. 2020 Feb 26;54(7):4356–4366. doi: 10.1021/acs.est.9b06089

Table 2. EDI [ng (kg BW)−1 day–1] of SCCPs, MCCPs, and LCCPs via Breastfeeding of Infants and MOE (Dimensionless) between the Lowest Doses Reported To Cause Adverse Toxicological Effects in Animals [LOEL, ng (kg BW)−1 day–1] and EDIsa.

    China Sweden Norway
    n = 36 n = 20 n = 8
lipid content (%) 3.81 4.07 4.74  
Conc (ng g−1 fat)
SCCPs 90th 543 21.6 24.3
  50th 35.0 12.8 10.2
MCCPs 90th 254 56.8 88.3
  50th 78.8 33.3 43.1
LCCPs 90th 34.9 8.62 10.8
  50th 8.80 4.89 4.26
EDI [ng (kg BW)–1day–1]
SCCPs 90th 2580 111 143
  50th 166 65 60
MCCPs 90th 374 291 519
  50th 121 170 253
LCCPs 90th 166 44 64
  50th 42 25 25
MOE (EU)
SCCPs 90th 891 20 700 16 100
MCCPs   96 300 124 000 69 400
MOE (EU)
SCCPs 50th 13 900 35 400 38 300
MCCPs   298 000 212 000 142 000
MOE (Canada)
MCCPs 90th 4960 20 600 11 600
LCCPs   428 000 1 610 000 1 120 000
MOE (Canada)
MCCPs 50th 16 000 35 200 23 700
LCCPs   1 680 000 2 830 000 2 830 000
a

The BMDL10 value for SCCPs and MCCPs proposed by EFSA is 2.3 and 36 mg (kg BW)−1 day–1, respectively.27 The LOEL value for MCCPs and LCCPs, respectively, proposed by ECCC is 6 and 71 mg (kg BW)−1 day–1.57