Table 2. EDI [ng (kg BW)−1 day–1] of SCCPs, MCCPs, and LCCPs via Breastfeeding of Infants and MOE (Dimensionless) between the Lowest Doses Reported To Cause Adverse Toxicological Effects in Animals [LOEL, ng (kg BW)−1 day–1] and EDIsa.
China | Sweden | Norway | ||
---|---|---|---|---|
n = 36 | n = 20 | n = 8 | ||
lipid content (%) | 3.81 | 4.07 | 4.74 | |
Conc (ng g−1 fat) | ||||
SCCPs | 90th | 543 | 21.6 | 24.3 |
50th | 35.0 | 12.8 | 10.2 | |
MCCPs | 90th | 254 | 56.8 | 88.3 |
50th | 78.8 | 33.3 | 43.1 | |
LCCPs | 90th | 34.9 | 8.62 | 10.8 |
50th | 8.80 | 4.89 | 4.26 | |
EDI [ng (kg BW)–1day–1] | ||||
SCCPs | 90th | 2580 | 111 | 143 |
50th | 166 | 65 | 60 | |
MCCPs | 90th | 374 | 291 | 519 |
50th | 121 | 170 | 253 | |
LCCPs | 90th | 166 | 44 | 64 |
50th | 42 | 25 | 25 | |
MOE (EU) | ||||
SCCPs | 90th | 891 | 20 700 | 16 100 |
MCCPs | 96 300 | 124 000 | 69 400 | |
MOE (EU) | ||||
SCCPs | 50th | 13 900 | 35 400 | 38 300 |
MCCPs | 298 000 | 212 000 | 142 000 | |
MOE (Canada) | ||||
MCCPs | 90th | 4960 | 20 600 | 11 600 |
LCCPs | 428 000 | 1 610 000 | 1 120 000 | |
MOE (Canada) | ||||
MCCPs | 50th | 16 000 | 35 200 | 23 700 |
LCCPs | 1 680 000 | 2 830 000 | 2 830 000 |