Table 1.
Baseline Characteristics for Patients with SCD (N = 3368)
| SCD Patients (N = 3368) | ||
|---|---|---|
| N | % | |
| Demographic Characteristics | ||
| Age (Mean±SD, Year) | 21.4 ± 14.9 | |
| Age Groups | ||
| 2–12 | 1231 | 36.6 |
| 13–17 | 407 | 12.1 |
| 18–24 | 524 | 15.6 |
| 25–34 | 555 | 16.5 |
| 35–44 | 335 | 10.0 |
| 45–54 | 234 | 7.0 |
| 55–63 | 82 | 2.4 |
| Gender | ||
| Female | 1832 | 54.4 |
| Male | 1536 | 45.6 |
| Race/Ethnicity | ||
| African American | 2386 | 70.8 |
| Caucasian | 97 | 2.9 |
| Hispanic | 181 | 5.4 |
| Asian | 23 | 0.7 |
| Others/unknown | 681 | 20.2 |
| Clinical Characteristics | ||
| Nonstudy SCD-Related Medication Use | ||
| Medication | ||
| Penicillin | 1399 | 41.5 |
| Folic acid | 1272 | 37.8 |
| Total number of nonstudy SCD medications | ||
| None | 1354 | 40.2 |
| 1 (either penicillin or folic acid) | 1357 | 40.3 |
| 2 (both penicillin and folic acid) | 657 | 19.5 |
| Blood Transfusion | ||
| Yes | 204 | 6.1 |
| No | 3164 | 93.9 |
| SCD-Related Complicationsa | ||
| Mean±SD | 2.5 ± 2.5 | |
| Yes | 2669 | 79.3 |
| No | 699 | 20.8 |
| SCD-Related Comorbiditiesa | ||
| Mean±SD | 0.5 ± 1.0 | |
| 0 | 2377 | 70.6 |
| 1 | 549 | 16.3 |
| 2 | 225 | 6.7 |
| 3+ | 217 | 6.4 |
| Charlson Comorbidity Index Scores | ||
| Mean±SD | 1.1 ± 1.8 | |
| 0 | 1675 | 49.7 |
| 1 | 913 | 27.1 |
| 2+ | 780 | 23.2 |
Abbreviation: SCD, sickle cell disease; SD, standard deviation.
a
The list of SCD-related complications and comorbidities can be found in Supplementary Material Tables S1 and S2, respectively.