Figure 4.
Rotarod performance of shiverer and control mice after S-AMPA injection. Performance (time on rotarod) is expressed as percentage of performance prior to injection. S-AMPA injection resulted in both groups in significant drop of performance at all concentrations compared to vehicle. Rotarod performance differed significantly between groups only at a S-AMPA concentration of 20 mM. Values shown are the mean ± SEM from two independent experiments with a total of 6 or 7 mice per data point. Asterisk indicates p<0.01, two-way ANOVA with Bonferroni post-tests.