Table 3. Comparison of the allele frequencies between the normal and hyperlipidemia groups [n (%)].
SNP | Allele | Normal (n=1248) | Hyperlipidmia (n=1248) | χ2 | P |
NCAN rs2238675 | C/T | 821(33.0)/1675(67.1) | 906(36.3)/1590(63.7) | 6.396 | 0.011 |
NCAN rs2228603 | C/T | 1505(60.3)/991(39.7) | 1368(54.8)/1128(45.2) | 15.390 | E-005 |
TM6SF2 rs58542926 | C/T | 1887(75.6)/609(24.4) | 1810(72.5)/686(27.5) | 6.182 | 0.013 |
TM6SF2 rs735273 | A/G | 2222(89.0)/274(11.0) | 2147(86.0)/349(14.0) | 10.316 | 0.001 |
CILP2 rs16996148 | G/T | 2211 (88.6)/285(11.4) | 1825(73.1)/671(26.9) | 192.770 | 4E-012 |
CILP2 rs17216525 | C/T | 565(22.6)/1931(77.4) | 420(16.8)/2076(83.2) | 26.592 | 3E-007 |
PBX4 rs12610185 | G/A | 1096(43.9)/1400(56.1) | 936(37.5)/1560(62.5) | 21.247 | 2E-007 |
SUGP1 rs10401969 | T/C | 1482(59.4)/1014(40.6) | 1565(62.7)/931(37.3) | 5.803 | 0.016 |
MAU2 rs73001065 | G/C | 561(22.5)/1935(77.5) | 673(27.0)/1823(73.0) | 13.503 | 9E-004 |
MAU2 rs8102280 | G/A | 1704(68.3)/792(31.7) | 1787(71.6)/709(28.4) | 6.563 | 0.010 |
MAU2 rs150268548 | G/A | 1065(42.7)/1431(57.3) | 924(37.0)/1572(63.0) | 16.616 | 6E-005 |
MAU2 rs968525 | C/T | 1031(41.3)/1465(58.7) | 951(38.1)/1545(61.9) | 5.355 | 0.021 |
NCAN: the neurocan gene. TM6SF2: the transmembrane 6 superfamily member 2 gene. CILP2: the cartilage intermediate layer protein 2 gene. PBX4: the PBX homeobox 4 gene. SUGP1: the SURP and G-patch domain containing 1 gene. MAU2: the MAU2 sister chromatid cohesion factor gene.