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. 2020 Jun 19;12(12):12422–12431. doi: 10.18632/aging.103354

Table 2. Cardiorenal syndrome classification system by Hatamizadeh et al.

CRS category (subclassified) Manifestation
Haemodynamic (acute/chronic) Renal dysfunction due to cardiac output
Uremic (acute/chronic) Uremic cardiomyopathy, Uremic pleuritis, Uremic pericarditis
Vascular (acute/chronic) Coronary artery disease, Renal artery thrombosis, Renal artery stenosis
Neurohumoral (acute/chronic) Abnormal serum calcium, potassium, magnesium and activated RAAS
Anemia and/or iron metabolism (acute/chronic) Iron deficiency, Renal tubularinjury, Infection, Folate deficiency
Mineral metabolism (mostly chronic) Vitamin D, Elevated FGF 23, Hypercalcemia, Hyperphosphatemia
Malnutrition/inflammation-cachexia (mostly chronic) Cachexia, malnutrition and inflammation

Abbreviations: RAAS: Renin-Angiotensin system, FGF-23: Fibroblast Growth Factor 23.