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. 2020 Jun 18;12(12):11603–11622. doi: 10.18632/aging.103320

Table 2. Echocardiography parameters (n=5 for each group).

		LVIDd, mm	LVIDs, mm	EF, %	FS, %
Sham	Baseline	7.80±0.19	3.93±0.18	86.25±2.13	51.02±2.58
Sham	ISO	7.48±0.13	1.71±0.07	98.50±0.09	78.00±0.99
	Rate of changes, %	-4.02±1.87	-56.19±2.79	14.41±2.76	53.89±6.29
HF	Baseline	9.34±0.36^*	7.00±0.39^*	55.17±2.16^*	25.29±1.35^*
HF	ISO	8.05±0.26^*	4.20±0.0.40^*	85.67±2.92^*	50.96±3.59^*
	Rate of changes, %	-13.63±2.16^*	-42.81±2.73^*	55.53±3.92^*	101.79±9.48^*
AD-EGFP	Baseline	9.60±0.26^*	7.30±0.22^*	54.90±0.84^*	24.24±0.44^*
AD-EGFP	ISO	8.41±0.22^*	4.04±0.25^*	86.52±1.45^*	52.62±1.80^*
	Rate of changes, %	-11.99±2.15^*	-45.41±2.58^*	58.01±3.46^*	108.36±7.43^*
AD-miR-145	Baseline	8.16±0.30^*#&	5.62±0.23^*#&	60.60±1.83^*#&	30.20±1.39^*#&
AD-miR-145	ISO	7.61±0.28^#&	3.15±0.0.35^*#&	88.73±0.86^*	54.07±1.08^*
	Rate of changes, %	-5.45±1.54^#	-44.26±3.78^*	42.16±4.31^*#&	80.25±7.47^*#&
M+C	Baseline	8.54±0.14^*#	5.99±0.16^*#	62.17±2.34^*#	29.83±1.56^*#
M+C	ISO	7.58±0.0.12^#	3.27±0.32^*#	89.44±1.21^*	56.17±2.02^*
	Rate of changes, %	-11.38±1.78^*	-45.67±3.61^*	44.65±4.32^*#	89.42±5.98^*#

^*P<0.05, compared with sham group; ^#P<0.05, compared with HF group; ^&P<0.05, compared with AD-EGFP group. Data are presented as mean ± SD.