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. 2020 Jun 18;12(12):11603–11622. doi: 10.18632/aging.103320

Table 3. ICa characteristics (n≥7).

Sham HF AD-EGFP AD-miR-145 M+C
ICa-peak decay time constant, ms
τ1 6.54±1.16 10.57±0.95* 10.46±1.13* 9.59±0.83* 10.46±0.89*
τ2 44.66±6.29 65.67±6.73* 65.96±9.44* 59.52±3.28* 62.01±8.51*
ICa activation kinetics
V1/2, mV -9.35 ±1.93 -4.18±2.26* -4.84±2.65* -6.67±1.54* -7.17±2.78*
K 3.65±0.38 4.65±0.36* 4.79±0.38* 4.18±0.24* 4.09±0.32*
ICa inactivation kinetics
V1/2, mV -19.56±1.35 -18.07±1.30 -17.57±2.48 -17.32±1.25 -17.88±2.03
K -1.45±2.01 0.16±3.06 -0.94±2.67 3.61±1.59 -0.84±2.39
ICa recovery time constant
τ, ms 101.55 144.36 154.39 111.31 120.86
±9.08 ±7.88* ±13.30* ±11.56#& ±3.37*#

V1/2: half-maximal activation or inactivation; K: slope factor; τ: time constant; *P<0.05, compared with sham group; #P<0.05, compared with HF group; &P<0.05, compared with AD-EGFP group. Data are presented as mean ± SEM.