Table 1. Characteristics of the rats at the end of the experiment.
| ZLRs (n=6) | ZLRs + Apigenin (n=4) | ZDFRs (n=6) | ZDFRs + Apigenin (n=6) | |
| Body weight (g) | 393.8±15.6 | 379.0±12.0 | 398.5±49.1 | 392.3±26.0 |
| HbA1c (%) | 3.47±0.05 | 3.42±0.09 | 10.4±0.18 * | 9.47±0.57 |
| Kidney weight (g) | 2.53±0.14 | 2.57±0.12 | 3.56±0.25 # | 3.38±0.18 |
| U-Alb/Cr (mg/gCr) | 0.018±0.001 | 0.010±0.003 | 1.52±1.00 * | 0.34±0.08 |
| U-L-FABP/Cr (ug/gCr) | 0.47±0.04 | 0.98±0.85 | 29.1±1.40 * | 7.61±4.40 |
| Cystatin C (ng/mL) | 0.92±0.04 | 1.13±0.06 | 1.14±0.07 | 1.04±0.12 |
| U-8-OHdG/Cr (ng/mgCr) | 9.30±1.33 | 7.30±2.00 | 43.6±20.9 * | 13.5±4.82 |
*p<0.01 vs. other groups. #p<0.01 vs. ZLRs and ZLRs + Apigenin.
ZLRs; Zucker lean rats, ZDFRs; Zucker diabetic fatty rats; U-Alb/Cr; urinary albumin/creatinine ratio, U-L-FABP; U-L-FABP/Cr; urinary liver-type free fatty acid binding protein/creatinine ratio, U-8-OHdG/Cr; urinary 8-hydroxy-2’-deoxyguanosine/creatinine ratio.