Table 2. Univariate and multivariate analyses of clinicopathological factors for overall survival of patients with clear cell renal cell carcinoma.

Risk factors	Univariate analysis		Multivariate analysis
	HR (95%CI)	P-value	HR (95%CI)	P-value
Age(years)	1.034(0.352-2.324)	0.914
Gender	0.942(0.565-2.905)	0.465
Clinical stage	1.789(1.019-4.856)	0.004	1.664(1.017-4.186)	0.028
Tumor stage	2.523(1.075-4.093)	0.007	2.081(1.128-3.597)	0.010
Distant metastasis	3.066(1.324-7.784)	0.000	2.866(1.324-6.784)	0.002
circ0085576 expression	1.476(1.098-5.889)	0.015	1.372(1.077-5.151)	0.032