Table 2. IC50 and combination index values in AML cell lines.

Treatment	Kasumi-1	MOLM13	OCI-AML2	OCI-AML3
Fasudil (IC50)	37.8μM	53.1μM	47.9μM	52.2μM
Sapanisertib (IC50)	2.1μM	1.3μM	0.4μM	0.6μM
Trametinib (IC50)	3.8nM	8.5nM	19.7nM	14.2nM
F-50μM + S-0.5μM (Combination index)	0.65	0.81	0.71	0.68
T-10nM + S-0.5μM (Combination index)	0.86	0.93	1.06	1.03
T-10nM + F-50μM (Combination index)	0.48	0.34	0.27	0.22