Table 2. Associations with longitudinal change in gait speed between baseline and follow up.
| Pathway | Metabolite | Beta (SE) | P-Value |
| Positive in Cross-Sectional Analysis | |||
| Lipid | |||
| Sphingolipid Metabolism | Behenoyl sphingomyelin (d18:1/22:0)* | 0.15 (0.06) | 0.02 |
| Sphingomyelin (40:2)* | 0.26 (0.07) | 2.6×10-4 | |
| Xenobiotics | |||
| Food Component/Plant | Ergothioneine | -0.05 (0.02) | 9.6×10-3 |
| Negative in Cross-Sectional Analysis | |||
| Amino Acid | |||
| Alanine and Aspartate Metabolism | N-acetylaspartate (NAA) | -0.13 (0.06) | 0.04 |
| Methionine, Cysteine, SAM and Taurine Metabolism | N-formylmethionine | -0.12 (0.05) | 0.01 |
| S-adenosylhomocysteine (SAH) | -0.03 (0.01) | 0.02 | |
| Phenylalanine Metabolism | 1-carboxyethylphenylalanine | -0.09 (0.02) | 8.8×10-5 |
| Carbohydrate | |||
| Aminosugar Metabolism | N-acetylneuraminate | -0.05 (0.03) | 0.04 |
| Nucleotide | |||
| Purine Metabolism, Guanine containing | N2,N2-dimethylguanosine | -0.05 (0.03) | 0.05 |
| Peptide | |||
| Gamma-glutamyl Amino Acid | Gamma-glutamylphenylalanine | -0.12 (0.05) | 0.03 |
* Indicates compounds with Metabolomics Standards Initiative confidence level 2.
2 unnamed metabolites are not shown.