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. 2020 Jun 17;12(12):11224–11237. doi: 10.18632/aging.103370

Table 3. Treatment of COVID-19 patients.

Total (n=238) Clinical classification *P value
Mild / General (n=190) Severe / Critical (n=48)
Complications, No. (%) 15 (6.3) 3 (1.6) 12 (25.0) <.001
Antiviral therapy, No. (%)
Lopinavir/Ritonavir alone 70 (29.3) 64 (33.7) 6 (12.5) 0.004
Lopinavir/Ritonavir + Interferon (analogues) 97 (40.8) 92 (48.4) 5 (10.4) <.001
Interferon (analogues) 35 (14.7) 32 (16.8) 3 (6.25) 0.06
Arbidol alone 16 (6.7) 11 (5.8) 5 (10.4) 0.33
Arbidol + Interferon (analogues) 11 (4.6) 11 (5.8) 0 (0) 0.13
Xuebijing (TCM) 17 (7.1) 10 (5.3) 7 (14.6) 0.03
Chloroquine phosphate 3 (1.3) 3 (1.6) 0 (0) >.99
Immunosuppressive therapy, No. (%)
Glucocorticoid therapy 76 (31.9) 28 (14.7) 48 (100) <.001
Gamma-globulin therapy 75 (31.5) 27 (14.2) 48 (100) <.001
Respiratory support, No. (%)
Oxygen inhalation 48 (20.2) 0 (0) 48 (100) <.001
Mechanic ventilation 4 (1.7) 0 (0) 4 (8.3) 0.002
ECMO 1 (0.4) 0 (0) 1 (2.1) 0.20

Abbreviations: TCM, traditional Chinese medicine; ECMO, extracorporeal membrane lung oxygenation.

* P values indicate differences between mild / general type and severe / critical patients. P < .05 was considered statistically significant.