Table 5. The impact of different drug management on the prognosis of mild/general and severe/critical patients.
| Candidate variables | Total (n=238) | Subgroups | ||||||
| Mild / General (n=190) | Severe / Critical (n=48) | |||||||
| *HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |||
| Antiviral therapy, | ||||||||
| Lopinavir/Ritonavir alone | Ref | Ref | Ref | |||||
| Lopinavir/Ritonavir + Interferon (analogues) | 1.31 (0.89, 1.93) | 0.17 | 1.29 (0.83, 2.00) | 0.25 | 0.55 (0.07, 4.12) | 0.56 | ||
| Interferon (analogues) | 0.95 (0.55, 1.64) | 0.85 | 0.82 (0.45, 1.50) | 0.52 | 3.35 (0.72, 15.65) | 0.12 | ||
| Arbidol alone | 1.44 (0.75, 2.75) | 0.27 | 2.13 (1.08, 4.20) | 0.03 | 4.18 (0.51, 34.28) | 0.18 | ||
| Arbidol + Interferon (analogues) | 2.50 (1.07, 5.83) | 0.03 | 2.29 (0.89, 5.84) | 0.08 | - | - | ||
| Xuebijing (TCM) | 1.51 (0.47, 4.83) | 0.49 | 0.99 (0.24, 4.11) | 0.99 | 40.99 (2.50, 670.88) | 0.01 | ||
| Chloroquine phosphate | 0.42 (0.06, 3.07) | 0.40 | 0.40 (0.06, 2.92) | 0.37 | - | - | ||
Abbreviations: TCM, traditional Chinese medicine, HR, hazard ratio; CI, confidence interval.
*HR values indicated the ratio of hazards of discharge among the patients with diverse antiviral therapy compared to the hazards of discharge among the patients with reference Lopinavir/Ritonavir alone treatment.