Table 1. Association of B7-H3 and CD47 expression with clinical characteristics and CD8⁺ T cell infiltration in patients with HCC.

Characteristic	Tumor B7-H3 Density/HPF#			P value	Tumor CD47 Density/HPF*		P value
	cases	Low	High		Low	High
	N	N (%)	N (%)		N (%)	N (%)
Gender
Female	11	4 (13.79)	7 (16.28)	1	8 (19.51)	3 (9.68)	0.413
Male	61	25 (86.21)	36 (83.72)		33 (80.49)	28 (90.32)
Age
<45	36	12 (41.38)	24 (55.81)	0.23	20 (48.78)	16 (51.61)	0.812
≥45	36	17 (58.62)	19 (44.19)		21 (51.22)	15 (48.39)
Tumor number
1	53	21 (72.41)	32 (74.42)	0.85	30 (73.17)	23 (74.19)	0.922
≥2	19	8 (27.59)	11 (25.58)		11 (26.83)	8 (25.81)
Tumor size
<1cm	48	16 (55.17)	32 (74.42)	0.089	26 (63.41)	22 (70.97)	0.501
≥1cm	24	13 (44.83)	11 (25.58)		15 (36.59)	9 (29.03)
Pathological Grade
Low/Moderate	41	17 (58.62)	24 (55.81)	0.841	27 (65.85)	14 (45.16)	0.079
High	31	12 (41.38)	19 (44.19)		14 (34.15)	17 (54.84)
Clinical Stage
stage I~II	50	20 (68.97)	30 (69.77)	0.942	32 (78.05)	18 (58.07)	0.068
stage III~IV	22	9 (31.03)	13 (30.23)		9 (21.95)	13 (41.93)
CD8 Expression
Low <10	43	22 (75.86)	21 (48.84)	0.0283	30 (73.17)	13 (41.93)	0.007
High ≥10	29	7 (24.14)	22 (51.16)		11 (26.83)	18 (58.07)

Note: ^# Tumor B7-H3 Density/HPF: <10% of tumor cells as low expression, ≥10% of tumor cells as high expression. *Tumor CD47 Density/HPF: <1% of tumor cells as low expression, ≥1% of tumor cells as high expression.