Table 1. A meta-analysis of miR expression profile in human DPN.

Author	Year	Country	Number		Age (mean ± standard deviation, year)		Gender (male/female)		miR
			DM	NC	DM	NC	DM	NC
Zhao H 26	2010	China	40	15	69 ± 13	54 ± 14	17/23	6/9	miR-375
Jiang LQ 27	2013	Sweden	24	29	60.1 ± 5.0	60.9 ± 4.7	18/6	19/10	miR-98, let-7b, let-7c, let-7f, let-7g, and let-7i
Pescador N 9	2013	China	99	100	69.4 ± 7.12	42.9 ± 12.13	53/46	50/50	miR-138, miR-376a, miR-15b, and miR-503
Zhang T 28	2013	China	30	30	63 ± 8.56	61 ± 9	16/14	16/14	miR-126
Liu Y 29	2014	China	160	138	50.2 ± 6.7	46.7 ± 7.2	78/82	67/71	miR-126
Ortega FJ 30	2014	Spain	30	35	54 ± 10	48.1 ± 10.1	30/0	35/0	miR-140-5p, miR-142-3p, miR-222, miR-423-5p, miR-125b, miR-192, miR-195, miR-130b, miR-532-5p, and miR-126
Sun K 31	2014	China	100	100	51.33 ± 11.75	48.55 ± 12.41	54/46	44/56	miR-375
Yang Z 32	2014	China	24	20	51.13 ± 9.214	46.65 ± 16.181	16/8	8/12	miR-23a
Al-Kafaji G 33	2015	Arabian	24	24	52 ± 6	49 ± 9.1	10/14	13/11	miR-15a
Olivieri F 34	2015	Italy	117	76	66.51 ± 7.48	64.25 ± 7.56	69/48	36/40	MiR-21-5p and miR-126a-3p
Wu L 35	2015	China	25	20	46.7 ± 8.6	45.5 ± 10.2	-	-	miR-152, miR-17, miR-138, and miR-593
Dai X 36	2015	China	85	80	57.4 ± 9.6	59.5 ± 13.5	44/41	43/37	miR-483-5p, miR-19a, miR-29a, miR-20a, miR-24, and miR-25
Wang C 37	2016	China	92	92	47.7 ± 13.9	50.2 ± 14.2	58/34	56/36	miR-661, miR-571, miR-770-5p, miR-892b, and miR-1303
Wu K 38	2016	China	14	21	44 ± 6	42 ± 5	-	-	miR-126
Yan S 39	2016	China	50	50	46.22 ± 6.897	45.52 ± 6.215	27/23	22/28	miR-1249, miR-572, miR-1249, and miR-572
Yang S 40	2016	China	58	30	49.8 ± 9.1	48.2 ± 8.9	-	-	miR-144 and miR-223

Note: DPN, diabetic peripheral neuropathy; DM, diabetes mellitus; NC, normal control; miR, microRNA.