Table 2.

The risk of eGFR<60 for parental and offspring in adulthood by famine exposure status.

	F1 generation		F2 generation
	Non-famine	Famine	Non-famine	Famine
Rate, %	12.76	23.21	14.70	16.74
OR (95% CI)
Model 1	1.00	1.66 (1.16, 2.77)	1.00	1.17 (0.83, 1.66)
Model 2	1.00	1.80 (1.10, 3.36)	1.00	1.26 (0.90, 1.75)

In the F1 generation, ORs (95% CIs) were calculated by the generalized mixed linear model with famine exposure (yes or no) as the fixed factor and family number as the random factor. Model 1 was adjusted for parental age and sex. Model 2 was adjusted as for Model 1 and for education, smoking, drinking, SBP, 2-hPG, working strength, daily energy intake, sport and BMI. In the F2 generation, ORs (95% CIs) were calculated by the generalized mixed linear model with parental famine exposure (yes or no) as the fixed factor and family number as the random factor. Model 1 was adjusted for offspring age and sex. Model 2 was adjusted as for Model 1 and for education, smoking, drinking, SBP, 2-hPG, working strength, daily energy intake, sport and BMI.