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. 2020 Jun 18;12(12):12206–12221. doi: 10.18632/aging.103397

Table 3.

Parental and offspring ΔeGFR in adulthood by famine exposure status.

F1 generation F2 generation
Coefficient (95%) P-Value Coefficient (95%) P-Value
Model1 -9.95 (-12.77, -7.13) <0.001 -6.15 (-11.83, -0.47) 0.035
Model2 -8.32 (-11.51, -5.12) <0.001 -6.11 (-11.88, -0.43) 0.034

In the F1 generation, coefficients and their 95% CIs were calculated by the mixed linear model with famine exposure (yes or no) as the fixed factor and family number as the random factor. Model 1 was adjusted for parental age and sex. Model 2 was adjusted as for Model 1 and for education, smoking, drinking, SBP, 2-hPG, working strength, daily energy intake, sport and BMI. In the F2 generation, coefficients and their 95% CIs were calculated by the mixed linear model with parental famine exposure (yes or no) as the fixed factor and family number as the random factor. Model 1 was adjusted for offspring age and sex. Model 2 was adjusted as for Model 1 and for education, smoking, drinking, SBP, 2-hPG, working strength, daily energy intake, sport and BMI.