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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Clin Endocrinol Metab. 2020 Jul 1;105(7):dgaa211. doi: 10.1210/clinem/dgaa211

Table 4.

Sensitivity analysis: adjusted associations of FPG, 2-hr PPPG, GDM status (according to WHO 1999 definition) at 26 weeks’ gestation with cIMT, cfPWV, AIx, AIx@75 SBP and DBP at age 6 years excluding preterm children or mothers with GDM or children with negative AIxa

SBP, mmHg
n = 452
DBP, mmHg
n = 452

β [CI 95%] β [CI 95%]

Unadjusted Adjusteda Unadjusted Adjusteda

FPG, mmol/L 1.75 [0.13; 3.37]b 1.52 [-0.23; 3.26] 0.09 [-1.12; 1.30] 0.17 [-1.16; 1.50]
2-hr PPPG, mmol/L -0.15 [-0.66; 0.37] -0.02 [-0.58; 0.54] -0.41[-0.79; -0.03]b -0.36 [-0.78; 0.07]
GDMc 0.48 [0.04 ; 0.92]b 0.66 [-1.36; 2.69] -0.10 [-0.42 ; 0.23] 0.20 [-1.33; 1.73]

a

Multiple linear and logistic regressions on multiple imputed datasets (n=20) also adjusted for study center, child’s sex, paternal height, maternal characteristics (ethnicity, age at delivery, height, pre-pregnancy BMI, educational attainment, BP category before 20 weeks of gestation, active smoking status at 26 weeks of gestation, exposure to tobacco at home and/or work in early pregnancy and at 26 weeks).

b

P-value<0.05.

c

GDM defined using WHO 1999 criteria.

Abbreviations: cIMT: carotid intima media thickness, cfPWV: carotid femoral pulse wave velocity, AIx: augmentation index, AIx@75: augmentation index normalized to a heart rate of 75 beats/min, SBP: systolic blood pressure, DBP: diastolic blood pressure, FPG: fasting plasma glucose, PPPG: postprandial plasma glucose, GDM: gestational diabetes mellitus.