Skip to main content
. Author manuscript; available in PMC: 2020 Jul 8.
Published in final edited form as: J Am Chem Soc. 2020 Mar 16;142(13):6268–6284. doi: 10.1021/jacs.0c00484

Figure 7.

Figure 7.

Crystal structures of AsqJ complexed with the 2-CF3 substrate analog. (A) and (B) Electron density maps and structures of the bound analog observed in space group P212121 (PDB code: 6KD9) and C2221 (PDB code: 6K3O), respectively. The 2Fo-Fc electron density maps (contoured at 1.0 σ) are shown in grey mesh. (C) Superimposition of the bound 2-CF3 analog. The conformations observed in space group P212121 and C2221, are in green and cyan, respectively. The orange-shaded region highlights the difference in ring-puckering seen in 2-CF3. (D) Structural comparison between AsqJ-bound 2-H (magenta) and 2-CF3 (green) in the orthorhombic crystal form (space group P212121) revealed the movement of 2-CF3 with respect to Fe, H134 and P132.