Table 1.
Demographic Characteristics, Study Base, Early-Onset Colorectal Cancer Cases, and Normal Colonoscopy Controls
| Variable | All Subjects n = 68,067 | EOCRC Cases n = 651 | Normal Colonoscopy Controls n = 67,416 |
|---|---|---|---|
| Age, mean (SD) | 43.2 (6.4) | 44.8 (4.9) | 43.2 (6.4) |
| Sex, n (%) | |||
| Male | 55,993 (82.3) | 594 (91.2) | 55,399 (82.2) |
| Female | 12,074 (17.7) | 57 (8.8) | 12,017 (17.8) |
| Race/Ethnicity, n (%) | |||
| White | 37,625 (55.3) | 364 (55.9) | 37,261 (55.3) |
| Black | 19,837 (29.1) | 193 (29.7) | 19,644 (29.1) |
| Asian | 1,087 (1.6) | 7 (1.1) | 1,080 (1.6) |
| American Indian | 463 (0.7) | ** | 462 (0.7) |
| Hispanic | 4,191 (6.2) | 32 (4.9) | 4,159 (6.2) |
| Other | 1,468 (2.2) | 15 (2.3) | 1,453 (2.2) |
| Unknown | 3,396 (5.0) | 39 (6.0) | 3,357 (5.0) |
| Diabetes, n (%) | |||
| Yes | 7,425 (10.9) | 68 (10.4) | 7,357 (10.9) |
| No | 60,642 (89.1) | 583 (89.6) | 60,059 (89.1) |
| Smoking Status, n (%) | |||
| Never | 21,108 (31.0) | 171 (26.3) | 20,937 (31.1) |
| Former | 7,499 (11.0) | 53 (8.1) | 7,446 (11.0) |
| Current | 18,887 (27.8) | 189 (29.0) | 18,698 (27.7) |
| Unknown | 20,573 (30.2) | 238 (36.6) | 20,335 (30.2) |
| Aspirin Use, n (%) | |||
| Yes | 10,254 (15.1) | 76 (11.7) | 10,178 (15.1) |
| No | 57,813 (84.9) | 575 (88.3) | 57,238 (84.9) |
| BMI, mean (SD) | 30.0 (5.6) | 29.5 (6.1) | 30.0 (5.6) |
| BMI Category, n (%) | |||
| Underweight | 298 (0.4) | 7 (1.1) | 291 (0.4) |
| Normal | 10,875 (16.0) | 131 (20.1) | 10,744 (15.9) |
| Overweight | 21,583 (31.7) | 189 (29.0) | 21,394 (31.7) |
| Obese | 27,549 (40.5) | 232 (35.6) | 27,317 (40.5) |
| Unknown | 7,762 (11.4) | 92 (14.1) | 7,670 (11.4) |
BMI, Body Mass Index; EOCRC, Early-Onset Colorectal Cancer; SD, Standard Deviation
**
Represents cell sample sizes <5