Table 1:

Summary Table.

Type of profiling	p53 status	# of unique cell lines	% cell lines w/ >100 genes deregulated (>2X)	% cell lines w/ p53 pathway activation	% cell lines w/ emergence or expansion of a p53 mutation (ΔAF>0.05)
Gene expression	WT	43	44.2%	32.6%	NA
	Mutant	122	43.4%	9.1%
WB + RT-qPCR	WT	5	NA	80%	NA
	Mutant	4		0%
Targeted DNA sequencing	WT	14	NA	NA	10%
	Mutant	26

Shown are the number of TP53-WT and TP53-mutant cell lines that were included in each experimental assay, the % of cell lines with > 100 genes deregulated by > 2 fold-change (FC), the % of cell lines with significant activation of the p53 pathway, and % of cell lines with emergence or expansion of a functional TP53 mutation (ΔAF > 0.05).