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. 2020 Jul 9;510:73–78. doi: 10.1016/j.cca.2020.07.007

Table 3.

Comparison of plasma and serum based anti-SARS-CoV-2 antibody detection.


Epitope
Euroimmun
Roche
Plasma
Serum
Plasma
Serum
Plasma
Serum
Absolute result Mean 0.90 0.90 4.00 4.40 14.00 7.50
Range −0.01–1.48 −0.023–1.48 0.35–8.63 0.35–9.69 0.08–56.7 0.08–42.7
Median 1.30 1.40 2.60 4.50 8.40 1.40
Kendalĺs tau 0.82 0.77 0.60
Mean bias (95% CI) −11.65% (-36.13% − 12.83%) 23.12% (-8.61% − 54.85%) −28.57% (-45.18% - −11.96%)



Interpreted result Overall Agreement (%) 100.00 90.0*/95.0# 100.00
Positive Agreement (%) 100.00 92.3*/100# 100.00
Negative Agreement (%) 100.00 85.7*/87.5# 100.00
Coheńs kappa 1.00 0.78 (0.49–1.07)*/0.89 (0.69–1.10)# 1.00