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. 2020 Jul 8;4:54. doi: 10.1186/s41687-020-00220-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Criterion Validity For Each Symptom Based on Kappa Statistics Overall (Mean) and by Assessment Day. Criterion validity for the seven treatment toxicity categories most commonly associated with EGFRI toxicity. Criterion validity is based on agreement between the FACT-EGFRI 18 and the CTCAE scoring systems, and was assessed both overall and by assessment day. Moderate or better agreement is defined as Kappa coefficients of ≥0.41